In this paper, a new sampling technique is proposed that can be used in the Multistart global optimization technique as well as techniques based on it. The new method takes a limited number of samples from the objective function and then uses them to train an Radial Basis Function (RBF) neural network. Subsequently, several samples were taken from the artificial neural network this time, and those with the smallest network value in them are used in the global optimization method. The proposed technique was applied to a wide range of objective functions from the relevant literature and the results were extremely promising.